Algorithms in Genome Research


392107 Jens Stoye Winter 2008/2009 Fr. 10-12 in U10-146 ekvv

Organisational Matters

Together with the practical course “Bioinformatische Anwendungen in der Genomforschung” in the following summer semester, this lecture forms the master module Algorithms in Genome Research.
The exercises will not be corrected or graded, but presence and activity during the exercise hours is expected. Credit points will be given based on an oral exam at the end of the semester.

Literature

The page AlgGRLiterature contains many links to the original literature.

Timetable

  • 17.10.2008: Organizational matters, overview
  • 24.10.2008: – no class–
  • 31.10.2008: Sequence assembly I: traditional, whole-genome shotgun
  • 07.11.2008: Sequence assembly II: short-read assembly, re-sequencing
  • 14.11.2008: Gene finding (tRNAs, pro and eu)
  • 21.11.2008: Patterns in non-coding regions
  • 28.11.2008: Transcriptomics I: DNA microarray design
  • 05.12.2008: Transcriptomics II: DNA microarray analysis
  • 12.12.2008: Proteomics I: 2D gels
  • 19.12.2008: Proteomics II: Analysis of mass spectra
  • 09.01.2009: Genome rearrangement I: Introduction
  • 16.01.2009: Genome rearrangement II: DCJ distance and sorting
  • 23.01.2009 at 9:00: Genome rearrangement III: HP distance
  • 23.01.2009 at 10:15: Genome rearrangement IV: Genome halving (by Marvin Meinold)
  • 30.01.2009: – no class –
  • 06.02.2009: Gene clusters

Exercises: Fr. 8:45 - 10:15 a.m. in U10-146

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